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Hotels in South America

From world-class luxury lodges to charming boutique hotels — handpicked stays across the continent.

El Cielo Hotel & Spa, Medellín ⭐ Featured
El Cielo Hotel & Spa, Medellín LUXURY · ★★★★★ · MEDELLíN

Medellín's most sophisticated hotel — a contemporary luxury property in the heart of El Poblado with the city's best spa, a roo...

Rooftop pool with Andean views El Cielo restaurant (Latin America 50 Best) Full-service spa Fitness centre Concierge and city tour service
$280 /night
📍 Medellín
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Patio del Mundo Hostel
Patio del Mundo Hostel BUDGET · ★★★ · MEDELLíN

The best-reviewed hostel in El Poblado — a social, well-run property with private rooms and dormitories in a colonial house with...

Free daily city orientation walk Rooftop terrace with city views Private rooms and dormitories Communal kitchen Social events programme
$22 /night
📍 Medellín
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Browse thousands of hotels, guesthouses and hostels across South America on Booking.com.

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How to Find the Best Deal

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Book Early

Patagonia and Galápagos lodges sell out months in advance. Book as early as possible for peak season.

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Travel Shoulder Season

April–May and September–October offer lower rates and fewer crowds at most destinations.

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Compare Rates

Always compare Booking.com, the hotel's own site, and specialist agents — rates vary significantly.